If you have an outdated version of Biosmart-Studio installed starting from v5.5, you can upgrade to the current version through several intermediate versions.
Make sure to backup your database before updating!

Note:

The update is performed over the installed version, i.e. no uninstallation required. Also, before updating, it's recommended to disable the antivirus and firewall.
Links to intermediate versions:

5.6.5 х86 https://drive.google.com/file/d/1wxeAOqYxfhcUAapdYK9itXTjAuw9Oktw/view?usp=sharing 

5.6.5 х64 https://drive.google.com/file/d/1KfJiX0cXc5Q_qLnmC8q-yra2_juanKqP/view?usp=sharing

5.7.5 х86  https://drive.google.com/file/d/1WcU5gICQ8DptvLoBeo9bEh_gSIkv9-WV/view?usp=sharing

5.7.5 х64 https://drive.google.com/file/d/1T2cJB8I4AqpEbaM6MeDeHkQyL488pcP7/view?usp=sharing

5.8.4 х86 https://drive.google.com/file/d/11rTDOx5mgSm2oTq3kYLX9Jrllh4jyFsg/view?usp=sharing 

5.8.4 х64 https://drive.google.com/file/d/1YE9ok2AXJ-SmHrelBlzYE7bpUkoNonO0/view?usp=sharing 

5.9.5 х86  https://drive.google.com/file/d/1B6PECQb7RwuJHX2Gu9AyZA8Hne0xqWHg/view?usp=sharing

5.9.5 х64 https://drive.google.com/file/d/1JMJpXHbrZRBODfoi4blfHg8Idfr-eFmi/view?usp=sharing 

5.10.9 x86 https://drive.google.com/file/d/1acKsiyI8QEiZrIKVBMtNgTLGnMRAFak2/view?usp=sharing

5.10.9 x64 https://drive.google.com/file/d/1Gw-QtUbKx8s9RKi-zewr97KTaqh2gToS/view?usp=sharing 

* Upgrading to Biosmart-Studio 6 version is also from version 5.10.x, but a license for version 6 is required.